Main

PhD Candidate, Cancer Biology and Genomics

University of Southern California, Los Angeles, CA

hideme

2018 — 2024

M.S. Translational Biotechnology

University of Southern California, Los Angeles, CA

hideme

2015 — 2018

B.A. Biology

University of Southern California, Los Angeles, CA

hideme

2009 — 2013

Doctoral Researcher

University of Southern California
PI: David Cobrinik

hideme

2018 — 2024

• Conducted studies of retinoblastoma transcriptomics by single cell analysis. Performed bioinformatic analyses of human retinal development and retinoblastoma cancer research in the laboratory of Dr. David Cobrinik at Children’s Hospital Los Angeles. Published one first-author and nine secondary author publications in which I led bioinformatics analyses.

Technician

Children’s Hospital Los Angeles
PI: David Cobrinik

hideme

2013 — 2018

• Conducted studies of retinoblastoma transcriptomics by single cell analysis. Performed bioinformatic analyses of human retinal development and retinoblastoma cancer research in the laboratory of Dr. David Cobrinik at Children’s Hospital Los Angeles. Published one first-author and nine secondary author publications in which I led bioinformatics analyses.

Undergraduate Research Assistant

University of Southern California
PI: John Tower

hideme

2012 — 2013

St. Baldrick’s

hideme

2019 — 2020

Stachelek, K., Harutyunyan, N., Lee, S., Beck, A., Kim, J., Xu, L., Berry, J. L., Nagiel, A., Reynolds, C. P., Murphree, A. L., Lee, T. C., Aparicio, J. G. & Cobrinik, D. Non-Synonymous, Synonymous, and Non-Coding Nucleotide Variants Contribute to Recurrently Altered Biological Processes During Retinoblastoma Progression. Genes Chromosomes Cancer (2022) doi:10.1002/gcc.23120.

N/A

2022

Li, H.-T., Xu, L., Weisenberger, D. J., Li, M., Zhou, W., Peng, C.-C., Stachelek, K., Cobrinik, D., Liang, G. & Berry, J. L. Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy. Nat Commun 13, 5523 (2022).

N/A

2022

Cambier, L., Stachelek, K., Triska, M., Jubran, R., Huang, M., Li, W., Zhang, J., Li, J. & Cobrinik, D. Extracellular vesicle-associated repetitive element DNAs as candidate osteosarcoma biomarkers. Sci Rep 11, 94 (2021).

N/A

2021

Kaneva, K., Merkurjev, D., Ostrow, D., Ryutov, A., Triska, P., Stachelek, K., Cobrinik, D., Biegel, J. A. & Gai, X. Detection of mitochondrial DNA variants at low level heteroplasmy in pediatric CNS and extra-CNS solid tumors with three different enrichment methods. Mitochondrion 51, 97–103 (2020).

N/A

2020

Berry, J. L., Xu, L., Kooi, I., Murphree, A. L., Prabakar, R. K., Reid, M., Stachelek, K., Le, B. H. A., Welter, L., Reiser, B. J., Chévez-Barrios, P., Jubran, R., Lee, T. C., Kim, J. W., Kuhn, P., Cobrinik, D. & Hicks, J. Genomic cfDNA analysis of aqueous humor in retinoblastoma predicts eye salvage: the surrogate tumor biopsy for retinoblastoma. Molecular Cancer Research 16, 1701–1712 (2018).

N/A

2018

Singh, H. P., Wang, S., Stachelek, K., Lee, S., Reid, M. W., Thornton, M. E., Craft, C. M., Grubbs, B. H. & Cobrinik, D. Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors. PNAS 115, E9391–E9400 (2018).

N/A

2018

Kim, J. W., Jacobsen, B., Zolfaghari, E., Ferrario, A., Chevez-Barrios, P., Berry, J. L., Lee, D. K., Rico, G., Madi, I., Rao, N., Stachelek, K., Wang, L.-C. & Gomer, C. Rabbit model of ocular indirect photodynamic therapy using a retinoblastoma xenograft. Graefe’s Archive for Clinical and Experimental Ophthalmology 255, (2017).

N/A

2017

Berry, J. L., Xu, L., Murphree, A. L., Krishnan, S., Stachelek, K., Zolfaghari, E., McGovern, K., Lee, T. C., Carlsson, A., Kuhn, P., Kim, J. W., Cobrinik, D. & Hicks, J. Potential of aqueous humor as a surrogate tumor biopsy for retinoblastoma. JAMA Ophthalmology 135, 1221–1230 (2017).

N/A

2017

Stachelek, K., Harutyunyan, N., Lee, S., Harutyunyan, A., Kim, J., Xu, L., Berry, J. L., Nagiel, A., Reynolds, C. P., Murphree, A. L., Lee, T. C., Aparicio, J. G. & Cobrinik, D. Non-Synonymous, synonymous, and non-coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression. Submitted.

N/A

2022

Shayler, D., Stachelek, K., Lee, S., Bai, J., Aparicio, J. G., Kim, Y., Singh, M., Bay, M., Thornton, M., Craft, C., Grubbs, B., Bonaguidi, M., Singh, H., & Cobrinik, David. Single cell transcriptomics reveals novel photoreceptor trajectories and a cancer-predisposed cone precursor state.

N/A

2022

Children’s Blood Disease Institute Annual Retreat 2022

N/A

2022

Biochemistry and Molecular Medicine Annual Retreat 2022

N/A

2022

The Saban Research Institute Science Day 2022

N/A

2022

Keystone Symposium 2019

N/A

2019